Cold Agglutinin Disease in Cats
 
This is a rare type II autoimmune disorder in which antibodies that attack red blood cells have enhanced activity at temperatures of less than 99° F (37.2° C). The term agglutinin refers to an antibody that causes antigens, such as red blood cells or bacteria, to adhere to each each other.
 
Cold agglutinins with low thermal capacity are usually associated with direct red blood cell agglutination (adhesion) at low body temperatures in the peripheral blood vessel network (i.e., the vessels outside of the main circulatory network). Cold l ...read more