Excessive Growth Hormone (Somatotropin) in Cats

Acromegaly in Cats
 
Acromegaly is a rare syndrome resulting from the excessive production of the growth hormone somatotropin by tumors in the anterior pituitary gland of adult cats. Clinical signs of this syndrome are a result of the hormone's direct catabolic (breaking down) and indirect anabolic (building up) effects. 
 
The anabolic effects, meanwhile, are mediated by somatomedin C (insulin-like growth factor I), which is secreted by the liver in response to growth hormone stimulation. The excessive levels of somatomedin C, however, promote protein synthesis and growth i ...read more

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